Dr. Alex Jimenez, El Paso's Chiropractor
I hope you have enjoyed our blog posts on various health, nutritional and injury related topics. Please don't hesitate in calling us or myself if you have questions when the need to seek care arises. Call the office or myself. Office 915-850-0900 - Cell 915-540-8444 Great Regards. Dr. J

As humans, we are constantly exposed to oxidative stress, mainly due to how we produce energy. For us, to live is to be in a constant oxidative process. But, what happens when we exceed our oxidative stress threshold or deal with a critical illness? Luckily, we have antioxidant mechanisms to counteract this deteriorating process, and we have food to provide fuel to this system. The dietary ingestion or high doses of antioxidant supplementation has become an excellent treatment to counteract oxidative stress associated with critical illness and pain reduction. 

Critical illness and oxidative stress.

Increased levels of oxidative stress are associated with critical illness or acute disease. The production of reactive oxygen species (ROS) and reactive nitrogen-oxygen species (RNOS) has a bidirectional effect. Indeed, ROS and RNOS are modulators of cell proliferation and signaling, apoptosis, and cell protection. However, in extensive doses, they can damage proteins, nucleic acids, polysaccharides, and polyunsaturated fatty acids, resulting in critical damage to cellular structure and, therefore, tissue dysfunction.

Mitochondrial dysfunction and inflammation

Mitochondrial dysfunction is a cornerstone of ROS production during critical illness or in septic shock. Other mechanisms enabling ROS production are the conversion of xanthine dehydrogenase to xanthine oxidase and the NAPDH oxidase enzyme stimulation in neutrophils and macrophages. Furthermore, elevated ROS/RNOS production upregulates the release of inflammatory cytokines from immune cells, activating inflammatory cascades and increasing adhesion molecules’ expression.

In addition, this inflammation upregulates the accumulation of granulocytes in different organ tissues, once again leading to increased ROS production. Consequently, this perpetuates the tissue injury and results in multiorgan dysfunction.

Pain and oxidative stress

Muscle pain or muscle soreness can be caused by strenuous or unaccustomed exercise and physical activity; it is commonly called delayed onset muscle soreness (DOMS). 

DOMS associates with exercise involving eccentric muscle action, such as generating muscle tension while controlling the muscle lengthen. Also, this type of injury or soreness is common in athletes returning to training after a prolonged time of inactivity. Furthermore, lactate accumulation, inflammation, muscle spasm, muscle damage, and connective tissue damage are the common denominators of DOMS. Again, oxidative stress is involved in all of these mechanisms mentioned above.

Furthermore, as exercise improves health, it can also increase oxidative stress partly due to increased oxygen consumption. Furthermore, engaging in repetitive or eccentric activity can increase inflammation. Therefore, antioxidant levels must be repleted to counteract the inflammatory and oxidative stress responses.

Antioxidants vs. Pain:

During the last ten years, researchers have investigated the efficacy of taking dietary supplements or antioxidant-enriched foods in elevated doses as a preventive treatment to stop or reduce muscle soreness after exercise. Furthermore, most studies use exogenous antioxidants such as vitamin C, vitamin E, polyphenols, glutathione, carotenoids, and coenzyme Q10 to improve antioxidant enzymatic function.

How to test it?

In El Paso Functional Medicine we evaluate our patient’s nutritional status with the ABC and D of nutritional assessment. Using the latest technology we are able to assess our patient’s antioxidant status, this allows us to create a personalized supplement protocol and dietary changes to improve our patient’s wellbeing.

 

Clinical application:

A review examining the effectiveness of antioxidants preventing muscle soreness after exercise reported the nest results:

  • When comparing antioxidant supplementation versus placebo, antioxidant supplementation reduced muscle soreness after 6, 24, and 48 hours after eccentric exercise. However, most of the studies used in this review had a different level of quality, making it difficult to determine the antioxidant efficacy.

Furthermore, the efficacy of high doses of antioxidants has been used in the ICU setting in sepsis shock and critically ill patients with exciting results. A review that included 11 articles reported the following results:

  • Antioxidant treatment resulted in a significant reduction in mortality. However, it did not reduce the risk of infection.
  • Studies that utilized a single trace element, such as selenium, were associated with a significant reduction in mortality.

It seems that we can’t get rid of stress! Even though exercise is a great way to deal with psychological stress, it can cause oxidative stress. Nevertheless, stress is not always bad. A decent amount of oxidative stress can push mitochondrial apoptosis and lead to better working mitochondria. Therefore, to keep stress at bay, we need to improve antioxidant function, and this can be taken care of by increasing dietary sources of antioxidants or supplementation. This article discussed the importance of antioxidant supplementation in different topics, one more critical than another. For instance, in critically ill patients, the best way to provide antioxidant supplementation is parenteral.

On the other hand, in DOMS, antioxidant supplementation slightly improved fatigue and pain symptoms after exercise compared to placebo. As a nutritionist, the turning point is the gastrointestinal function, critically ill patients are overmedicated, which can diminish their capacity to absorb nutrients while athletes are healthy. Nutrient depletion is present in both of these situations, but the digestive system plays a critical role in absorbing these cofactors. – Ana Paola Rodríguez Arciniega, MS

 

References:

Ranchordas, Mayur K et al. “Antioxidants for preventing and reducing muscle soreness after exercise.” The Cochrane database of systematic reviews vol. 12,12 CD009789. 14 Dec. 2017, doi:10.1002/14651858.CD009789.pub2

Koekkoek, W A C Kristine, and Arthur R H van Zanten. “Antioxidant Vitamins and Trace Elements in Critical Illness.” Nutrition in clinical practice: official publication of the American Society for Parenteral and Enteral Nutrition vol. 31,4 (2016): 457-74. doi:10.1177/0884533616653832

Additional Online Links & Resources (Available 24/7)

 

Online Appointments or Consultations: bit.ly/Book-Online-Appointment

 

Online Physical Injury / Accident Intake Form: bit.ly/Fill-Out-Your-Online-History 

 

Online Functional Medicine Assessment: bit.ly/functionmed

 

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Professional Scope of Practice *

The information herein on "Antioxidants vs. Pain and Illness" is not intended to replace a one-on-one relationship with a qualified health care professional or licensed physician and is not medical advice. We encourage you to make healthcare decisions based on your research and partnership with a qualified healthcare professional.

Blog Information & Scope Discussions

Our information scope is limited to Chiropractic, musculoskeletal, acupuncture, physical medicines, wellness, contributing etiological viscerosomatic disturbances within clinical presentations, associated somatovisceral reflex clinical dynamics, subluxation complexes, sensitive health issues, and/or functional medicine articles, topics, and discussions.

We provide and present clinical collaboration with specialists from various disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system.

Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and directly or indirectly support our clinical scope of practice.*

Our office has reasonably attempted to provide supportive citations and has identified the relevant research studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.

We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez, DC, or contact us at 915-850-0900.

We are here to help you and your family.

Blessings

Dr. Alex Jimenez DC, MSACP, RN*, CCST, IFMCP*, CIFM*, ATN*

email: coach@elpasofunctionalmedicine.com

Licensed as a Doctor of Chiropractic (DC) in Texas & New Mexico*
Texas DC License # TX5807, New Mexico DC License # NM-DC2182

Licensed as a Registered Nurse (RN*) in Florida
Florida License RN License # RN9617241 (Control No. 3558029)
Compact Status: Multi-State License: Authorized to Practice in 40 States*

Presently Matriculated: ICHS: MSN* FNP (Family Nurse Practitioner Program)

Dr. Alex Jimenez DC, MSACP, RN* CIFM*, IFMCP*, ATN*, CCST
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Our Purpose & Passions: I am a Doctor of Chiropractic specializing in progressive, cutting-edge therapies and functional rehabilitation procedures focused on clinical physiology, total health, practical strength training, and complete conditioning. We focus on restoring normal body functions after neck, back, spinal and soft tissue injuries.

We use Specialized Chiropractic Protocols, Wellness Programs, Functional & Integrative Nutrition, Agility & Mobility Fitness Training, and Rehabilitation Systems for all ages.

As an extension to effective rehabilitation, we too offer our patients, disabled veterans, athletes, young and elder a diverse portfolio of strength equipment, high-performance exercises, and advanced agility treatment options. We have teamed up with the cities premier doctors, therapists, and trainers to provide high-level competitive athletes the possibilities to push themselves to their highest abilities within our facilities.

We’ve been blessed to use our methods with thousands of El Pasoans over the last three decades allowing us to restore our patients’ health and fitness while implementing researched non-surgical methods and functional wellness programs.

Our programs are natural and use the body’s ability to achieve specific measured goals, rather than introducing harmful chemicals, controversial hormone replacement, unwanted surgeries, or addictive drugs. We want you to live a functional life that is fulfilled with more energy, a positive attitude, better sleep, and less pain. Our goal is to ultimately empower our patients to maintain the healthiest way of living.

With a bit of work, we can achieve optimal health together, no matter the age or disability.

Join us in improving your health for you and your family.

It’s all about: LIVING, LOVING & MATTERING!

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EL PASO LOCATIONS

East Side: Main Clinic*
11860 Vista Del Sol, Ste 128
Phone: 915-412-6677

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6440 Gateway East, Ste B
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Phone: 915-412-6677

Dr. Alex Jimenez DC, MSACP, CIFM, IFMCP, ATN, CCST
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Additional Online Links & Resources (Available 24/7)

  1. Online Appointments or Consultations:  bit.ly/Book-Online-Appointment
  2. Online Physical Injury / Accident Intake Form:  bit.ly/Fill-Out-Your-Online-History
  3. Online Functional Medicine Assessment:  bit.ly/functionmed

Disclaimer *

The information herein is not intended to replace a one-on-one relationship with a qualified health care professional, licensed physician, and is not medical advice. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional. Our information scope is limited to chiropractic, musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present clinical collaboration with specialists from a wide array of disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system. Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and support, directly or indirectly, our clinical scope of practice.* Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.

We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, ATN*

email: coach@elpasofunctionalmedicine.com

phone: 915-850-0900

Licensed in Texas & New Mexico *

Dr. Alex Jimenez DC, MSACP, CIFM, IFMCP, ATN, CCST
My Digital Business Card

Post Disclaimer

Professional Scope of Practice *

The information herein on "Periscapular Bursitis: How to Relieve Pain and Discomfort" is not intended to replace a one-on-one relationship with a qualified health care professional or licensed physician and is not medical advice. We encourage you to make healthcare decisions based on your research and partnership with a qualified healthcare professional.

Blog Information & Scope Discussions

Our information scope is limited to Chiropractic, musculoskeletal, acupuncture, physical medicines, wellness, contributing etiological viscerosomatic disturbances within clinical presentations, associated somatovisceral reflex clinical dynamics, subluxation complexes, sensitive health issues, and/or functional medicine articles, topics, and discussions.

We provide and present clinical collaboration with specialists from various disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system.

Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and directly or indirectly support our clinical scope of practice.*

Our office has reasonably attempted to provide supportive citations and has identified the relevant research studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.

We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez, DC, or contact us at 915-850-0900.

We are here to help you and your family.

Blessings

Dr. Alex Jimenez DC, MSACP, RN*, CCST, IFMCP*, CIFM*, ATN*

email: coach@elpasofunctionalmedicine.com

Licensed as a Doctor of Chiropractic (DC) in Texas & New Mexico*
Texas DC License # TX5807, New Mexico DC License # NM-DC2182

Licensed as a Registered Nurse (RN*) in Florida
Florida License RN License # RN9617241 (Control No. 3558029)
Compact Status: Multi-State License: Authorized to Practice in 40 States*

Presently Matriculated: ICHS: MSN* FNP (Family Nurse Practitioner Program)

Dr. Alex Jimenez DC, MSACP, RN* CIFM*, IFMCP*, ATN*, CCST
My Digital Business Card