Dr. Alex Jimenez, El Paso's Chiropractor
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Folate, and its synthetic form folic acid, is a water-soluble B vitamin that plays a fundamental role in a variety of functions in the human body. Folate is essential for cell division and homeostasis because it acts as a coenzyme in many biological pathways, including amino acid metabolism, methionine production, and DNA methylation. Folate metabolism happens together with the methionine cycle and the choline pathway. Most folate coenzymes are found in the liver.

 

Folate is also used as a coenzyme to convert methionine into homocysteine. Vitamin B6 and B12, together with folate, are also essential for DNA synthesis. Proper dietary intake of folate is fundamental for normal cell growth and DNA repair. Folate or vitamin B12 deficiency can ultimately cause a variety of health issues, including anemia. Oral supplementation may be necessary. In the following article, we will discuss folate metabolism and foods that are high in folate.

 

Folate Metabolism Overview

 

Several of the most important functions of folate metabolism are methylation and S-adenosylmethionine (SAM) production, one of the most essential methyl donors in the cell. In the following diagram, we will explain folate metabolism. 

 

Image of a folate metabolism diagram.

 

Figure 1: One carbon metabolism. ATP: adenosyl triphosphate, B6: vitamin B6, B12: vitamin B12, BHMT: betaine homocysteine methyltransferase, CBS: cystathionine-?-synthase, DHF: dihydrofolate, DMG: dimethylglycine, dTMP: deoxythymidine monophosphate, dUMP: deoxyuridine monophosphate, Gly: glycine, Hcy: homocysteine, MAT: methionine adenosyltransferase, Met: methionine, MCM: L-methylmalonyl CoA mutase, MM-CoA: L-methylmalonyl CoA, MMA: methylmalonic acid, MS: methionine synthase, MTHFR: 5,10-methyltetrahydrofolate reductase, SAH: S-adenosyl homocysteine, SAHH: S-adenosyl homocysteine hydrolase, SAM: S-adenosyl methionine, Ser: serine, SHMT, serine hydroxymethyltransferase, THF: tetrahydrofolate, TS: thymidylate synthase. Adapted from: Hypo- and hypervitaminosis of B and D vitamins – Diagnosis and clinical consequences. Herrmann W. et al. 2013. Uni-Med Verlag AG.

 

Dihydrofolate reductase (DHFR) is a component that converts folate to dihydrofolate (DHF) and DHF to the active form, THF. Folate metabolism consists of three cycles. One cycle starts with a component known as 10-formylTHF which is associated with purine production and two cycles utilize 5, 10-methyleneTHF in deoxythymidine monophosphate (dTMP) and methionine production. 5-MethylTHF is one of the most predominant forms of folate found in the human body.

 

After cellular uptake, 5-methylTHF is converted into THF through the use of vitamin B12 in methionine synthase (MS). The methionine cycle is a fundamental pathway in SAM production. As previously mentioned above, B vitamin deficiencies, including folate, vitamin B6, and B12, as well as genetic birth defects can ultimately cause a variety of health issues. 5,10-MethyleneTHF is finally converted to 5-methylTHF by 5,10-methylenetetrahydrofolate reductase (MTHFR).

 

Several of the most important functions of folate metabolism are methylation and S-adenosylmethionine (SAM) production, one of the most essential methyl donors in the cell. In the following diagram, we will simplify folate metabolism. 

 

Image of a second folate metabolism diagram.

 

15 Foods That Are High in Folate

 

Folate, and its synthetic form folic acid, is a water-soluble B vitamin that plays a fundamental role in a variety of functions in the human body. It supports cell division and promotes fetal growth and development to reduce the risk of genetic birth defects. Folate is naturally found in many different types of foods. Doctors recommend 400 mcg of folate every day for adults to prevent deficiency. Here are 15 healthy foods that are high in folate or folic acid, including:

 

  • avocado
  • bananas
  • citrus fruits
  • papaya
  • beets
  • leafy greens
  • asparagus
  • Brussels sprouts
  • broccoli
  • nuts and seeds
  • legumes
  • eggs
  • beef liver
  • wheat germ
  • fortified grains

 

In conclusion, folate, and its synthetic form folic acid, is an important micronutrient that can be naturally found in many different types of foods. Eating many different types of healthy foods, including fruits, vegetables, nuts, and seeds, as well as fortified foods, is an easy way to increase your folate intake. These foods are not only high in folate but these are also high in other essential nutrients that can ultimately improve other aspects of your overall health.

 

For information regarding the nutritional role of folate, please review the following article:

Nutritional Role of Folate

 


 

Folate or folic acid is a water-soluble B vitamin that plays a fundamental role in a variety of functions in the human body, including cell division and homeostasis. Folate also helps with amino acid metabolism, methionine production, and DNA methylation. Folate or vitamin B12 deficiency can ultimately cause a variety of health issues. Oral supplementation may be necessary. In the diagrams above, we explain the process of folate metabolism. Folate is naturally found in many different types of foods, including avocado, citrus fruits, leafy greens, broccoli, nuts and seeds, legumes, eggs, and fortified grains. Eating many different types of healthy foods is an easy way to increase your folate intake. These foods are not only high in folate but these are also high in other essential nutrients that can ultimately improve other aspects of your overall health. – Dr. Alex Jimenez D.C., C.C.S.T. Insights

 


 

Image of the Berry Bliss Smoothie

 

Berry Bliss Smoothie

Servings: 1
Cook time: 5-10 minutes

• 1/2 cup blueberries (fresh or frozen, preferably wild)
• 1 medium carrot, roughly chopped
• 1 tablespoon ground flaxseed or chia seed
• 1 tablespoons almonds
• Water (to desired consistency)
• Ice cubes (optional, may omit if using frozen blueberries)

Blend all ingredients in a high-speed blender until smooth and creamy. Best served immediately.

 


 

Image of Almonds.

 

Almonds have twice as much calcium as milk

 

Gram for gram this is absolutely true! According to McCance and Widdowson’s Composition of Foods (the official guide to the nutrients in food used in the UK), about 100g of almonds have 240mg of bone-building calcium while semi-skimmed (2%) milk has 120mg per 100g (3.5oz). With that being said, however, we tend to drink milk in bigger quantities than we eat almonds (and the calcium from milk is easily absorbed), so the dairy option may be a better source day-to-day.

 


 

The scope of our information is limited to chiropractic, musculoskeletal, physical medicines, wellness, and sensitive health issues and/or functional medicine articles, topics, and discussions. We use functional health & wellness protocols to treat and support care for injuries or disorders of the musculoskeletal system. Our posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate and support directly or indirectly our clinical scope of practice.* Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. We understand that we cover matters that require an additional explanation as to how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900. The provider(s) Licensed in Texas*& New Mexico* 

 

Curated by Dr. Alex Jimenez D.C., C.C.S.T.

 

References:

 

 

Post Disclaimer

Professional Scope of Practice *

The information herein on "What is Folate Metabolism?" is not intended to replace a one-on-one relationship with a qualified health care professional or licensed physician and is not medical advice. We encourage you to make healthcare decisions based on your research and partnership with a qualified healthcare professional.

Blog Information & Scope Discussions

Our information scope is limited to Chiropractic, musculoskeletal, acupuncture, physical medicines, wellness, contributing etiological viscerosomatic disturbances within clinical presentations, associated somatovisceral reflex clinical dynamics, subluxation complexes, sensitive health issues, and/or functional medicine articles, topics, and discussions.

We provide and present clinical collaboration with specialists from various disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system.

Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and directly or indirectly support our clinical scope of practice.*

Our office has reasonably attempted to provide supportive citations and has identified the relevant research studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.

We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez, DC, or contact us at 915-850-0900.

We are here to help you and your family.

Blessings

Dr. Alex Jimenez DC, MSACP, RN*, CCST, IFMCP*, CIFM*, ATN*

email: coach@elpasofunctionalmedicine.com

Licensed as a Doctor of Chiropractic (DC) in Texas & New Mexico*
Texas DC License # TX5807, New Mexico DC License # NM-DC2182

Licensed as a Registered Nurse (RN*) in Florida
Florida License RN License # RN9617241 (Control No. 3558029)
Compact Status: Multi-State License: Authorized to Practice in 40 States*

Presently Matriculated: ICHS: MSN* FNP (Family Nurse Practitioner Program)

Dr. Alex Jimenez DC, MSACP, RN* CIFM*, IFMCP*, ATN*, CCST
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Our Purpose & Passions: I am a Doctor of Chiropractic specializing in progressive, cutting-edge therapies and functional rehabilitation procedures focused on clinical physiology, total health, practical strength training, and complete conditioning. We focus on restoring normal body functions after neck, back, spinal and soft tissue injuries.

We use Specialized Chiropractic Protocols, Wellness Programs, Functional & Integrative Nutrition, Agility & Mobility Fitness Training, and Rehabilitation Systems for all ages.

As an extension to effective rehabilitation, we too offer our patients, disabled veterans, athletes, young and elder a diverse portfolio of strength equipment, high-performance exercises, and advanced agility treatment options. We have teamed up with the cities premier doctors, therapists, and trainers to provide high-level competitive athletes the possibilities to push themselves to their highest abilities within our facilities.

We’ve been blessed to use our methods with thousands of El Pasoans over the last three decades allowing us to restore our patients’ health and fitness while implementing researched non-surgical methods and functional wellness programs.

Our programs are natural and use the body’s ability to achieve specific measured goals, rather than introducing harmful chemicals, controversial hormone replacement, unwanted surgeries, or addictive drugs. We want you to live a functional life that is fulfilled with more energy, a positive attitude, better sleep, and less pain. Our goal is to ultimately empower our patients to maintain the healthiest way of living.

With a bit of work, we can achieve optimal health together, no matter the age or disability.

Join us in improving your health for you and your family.

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Phone: 915-412-6677

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Dr. Alex Jimenez DC, MSACP, CIFM, IFMCP, ATN, CCST
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Disclaimer *

The information herein is not intended to replace a one-on-one relationship with a qualified health care professional, licensed physician, and is not medical advice. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional. Our information scope is limited to chiropractic, musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present clinical collaboration with specialists from a wide array of disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system. Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and support, directly or indirectly, our clinical scope of practice.* Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.

We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, ATN*

email: coach@elpasofunctionalmedicine.com

phone: 915-850-0900

Licensed in Texas & New Mexico *

Dr. Alex Jimenez DC, MSACP, CIFM, IFMCP, ATN, CCST
My Digital Business Card

Post Disclaimer

Professional Scope of Practice *

The information herein on "The Role of Chiropractic Care on improving your Health | El Paso, Tx (2023)" is not intended to replace a one-on-one relationship with a qualified health care professional or licensed physician and is not medical advice. We encourage you to make healthcare decisions based on your research and partnership with a qualified healthcare professional.

Blog Information & Scope Discussions

Our information scope is limited to Chiropractic, musculoskeletal, acupuncture, physical medicines, wellness, contributing etiological viscerosomatic disturbances within clinical presentations, associated somatovisceral reflex clinical dynamics, subluxation complexes, sensitive health issues, and/or functional medicine articles, topics, and discussions.

We provide and present clinical collaboration with specialists from various disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system.

Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and directly or indirectly support our clinical scope of practice.*

Our office has reasonably attempted to provide supportive citations and has identified the relevant research studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.

We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez, DC, or contact us at 915-850-0900.

We are here to help you and your family.

Blessings

Dr. Alex Jimenez DC, MSACP, RN*, CCST, IFMCP*, CIFM*, ATN*

email: coach@elpasofunctionalmedicine.com

Licensed as a Doctor of Chiropractic (DC) in Texas & New Mexico*
Texas DC License # TX5807, New Mexico DC License # NM-DC2182

Licensed as a Registered Nurse (RN*) in Florida
Florida License RN License # RN9617241 (Control No. 3558029)
Compact Status: Multi-State License: Authorized to Practice in 40 States*

Presently Matriculated: ICHS: MSN* FNP (Family Nurse Practitioner Program)

Dr. Alex Jimenez DC, MSACP, RN* CIFM*, IFMCP*, ATN*, CCST
My Digital Business Card