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Newly Discovered Compound Found to Reverse Aging

Medical researchers have discovered a naturally occurring compound the human body produces that can speed DNA repair, combat disease, and may turn back the clock on aging.

The compound — called NAD+, which is present in all cells — plays a key role in regulating protein interactions that control DNA repair.

An international group of scientists predicts the team’s discovery of NAD+ will lead to a new drug to reverse aging, speed DNA repair, and even keep astronauts healthy on long space flights.

A leading member of research team — geneticist Dr. David Sinclair, whose team is based at Harvard Medical School and the University of New South Wales in Sydney, Australia — said the first human trials of a therapy based on the compound will begin within six months.

Twenty-five volunteers will be injected with a substance to verify its health and longevity benefits. If the trial turns out successfully, larger scale human trials will be conducted in the United States, Australia, and possibly other countries.

“Then we really get serious,” Sinclair tells Newsmax Health.

NAD+ is what’s known as a metabolite — a substance naturally found in our bodies which are vital for metabolism. It is present in all cells and plays a key role as a regulator in protein-to-protein interactions controlling DNA repair.

Sinclair’s laboratory research involved using NMN — a NAD+ precursor or “booster” — which the team has shown is successful in improving cells’ ability to repair DNA damage caused by radiation exposure (including sunlight) and old age.

The team’s lab work found that mice, injected with NMN, appeared more youthful — at the cellular level — in a variety of standard biological tests.

“The cells of the old mice were indistinguishable from the young mice after just one week of treatment,” Sinclair says.

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“This is the closest we’ve come to a safe and effective anti-aging drug that’s perhaps only three to five years away from being on the market, if the [human] trials go well.”

The research project has come to the attention of the National Aeronautics and Space Administration (NASA), which has asked to be kept fully briefed on progress because of the possibility of using the substance to keep its astronauts healthy during long space missions, which can speed up aging processes.

Another group that stands to benefit: Survivors of childhood cancers.

According to Dr. Lindsay Wu, a University of New South Wales-based member of the research team, 96 percent of childhood cancer survivors suffer a chronic disease by age 45.

These include cardiovascular diseases, Type 2 diabetes, Alzheimer’s disease, and various cancers unrelated to their childhood cancers.

“All of this adds up to the fact they have accelerated aging — which is devastating,” Wu says. “It would be great to do something about that — and we believe we can with this molecule.”

For the past four years, Sinclair, Wu, and others on the research team have been working with biomedical companies with the aim of making NMN into a drug substance that can be used on patients. It will act by boosting the effectiveness of the body’s own NAD+.

The research was reported in a recent issue of the journal Science.

As well as delaying the onset of visible signs of aging, Sinclair believes the compound could have a great “impact on health and longevity.”

“We took mice that were 20 months old, which is equivalent to a 60- [to] 70 year-old human and we gave them NMN and we found that . . . many aspects of aging were reversed,” Sinclair notes.

“Their DNA repair activities went up to youthful levels and they were more resistant to radiation and should therefore be more protected against cancer and aging itself.”

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The information herein on "Newly Discovered Compound Found to Reverse Aging" is not intended to replace a one-on-one relationship with a qualified health care professional or licensed physician and is not medical advice. We encourage you to make healthcare decisions based on your research and partnership with a qualified healthcare professional.

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Our information scope is limited to Chiropractic, musculoskeletal, acupuncture, physical medicines, wellness, contributing etiological viscerosomatic disturbances within clinical presentations, associated somatovisceral reflex clinical dynamics, subluxation complexes, sensitive health issues, and/or functional medicine articles, topics, and discussions.

We provide and present clinical collaboration with specialists from various disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system.

Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and directly or indirectly support our clinical scope of practice.*

Our office has reasonably attempted to provide supportive citations and has identified the relevant research studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.

We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez, DC, or contact us at 915-850-0900.

We are here to help you and your family.

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Dr. Alex Jimenez DC, MSACP, RN*, CCST, IFMCP*, CIFM*, ATN*

email: coach@elpasofunctionalmedicine.com

Licensed as a Doctor of Chiropractic (DC) in Texas & New Mexico*
Texas DC License # TX5807, New Mexico DC License # NM-DC2182

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Disclaimer *

The information herein is not intended to replace a one-on-one relationship with a qualified health care professional, licensed physician, and is not medical advice. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional. Our information scope is limited to chiropractic, musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present clinical collaboration with specialists from a wide array of disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system. Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and support, directly or indirectly, our clinical scope of practice.* Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.

We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, ATN*

email: coach@elpasofunctionalmedicine.com

phone: 915-850-0900

Licensed in Texas & New Mexico *

Dr. Alex Jimenez DC, MSACP, CIFM, IFMCP, ATN, CCST
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Post Disclaimer

Professional Scope of Practice *

The information herein on "Home Exercises for Pain Relief | El Paso, Tx (2023)" is not intended to replace a one-on-one relationship with a qualified health care professional or licensed physician and is not medical advice. We encourage you to make healthcare decisions based on your research and partnership with a qualified healthcare professional.

Blog Information & Scope Discussions

Our information scope is limited to Chiropractic, musculoskeletal, acupuncture, physical medicines, wellness, contributing etiological viscerosomatic disturbances within clinical presentations, associated somatovisceral reflex clinical dynamics, subluxation complexes, sensitive health issues, and/or functional medicine articles, topics, and discussions.

We provide and present clinical collaboration with specialists from various disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system.

Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and directly or indirectly support our clinical scope of practice.*

Our office has reasonably attempted to provide supportive citations and has identified the relevant research studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.

We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez, DC, or contact us at 915-850-0900.

We are here to help you and your family.

Blessings

Dr. Alex Jimenez DC, MSACP, RN*, CCST, IFMCP*, CIFM*, ATN*

email: coach@elpasofunctionalmedicine.com

Licensed as a Doctor of Chiropractic (DC) in Texas & New Mexico*
Texas DC License # TX5807, New Mexico DC License # NM-DC2182

Licensed as a Registered Nurse (RN*) in Florida
Florida License RN License # RN9617241 (Control No. 3558029)
Compact Status: Multi-State License: Authorized to Practice in 40 States*

Presently Matriculated: ICHS: MSN* FNP (Family Nurse Practitioner Program)

Dr. Alex Jimenez DC, MSACP, RN* CIFM*, IFMCP*, ATN*, CCST
My Digital Business Card