Dr. Alex Jimenez, El Paso's Chiropractor
I hope you have enjoyed our blog posts on various health, nutritional and injury related topics. Please don't hesitate in calling us or myself if you have questions when the need to seek care arises. Call the office or myself. Office 915-850-0900 - Cell 915-540-8444 Great Regards. Dr. J

Manipulation and Immunity: WHO & WFC Immediately Response

Ethics and Integrity Can Not be Separated

INSIGHT: Many Chiropractors claim that immunity is increased by manipulating the spine. This claim has immediately created a need to substantiate its source. The WFC and WHO has responded in stealth to seek out the sourcing in order to bring clarity on the matter. The following guidelines have been mandated and supported by the Texas Board of Chiropractic. I too agree with this mini-meta review and mandate.

Dr Alex Jimenez DC Licensed Texas & New Mexico

The Effect of Spinal Adjustment / Manipulation on Immunity and the Immune System: A Rapid Review of Relevant Literature.

World Federation of Chiropractic. March 19, 2020

The Effect of Spinal Adjustment / Manipulation on Immunity and the Immune System: A Rapid Review of the Relevant Literature

World Federation of Chiropractic. March 19, 2020

Introduction

The world is currently in the midst of a global health crisis due to the spread of Coronavirus Disease 2019 (COVID-19). The World Health Organization (WHO) has declared COVID-19 a pandemic, meaning that it is being spread uncontrolled across country borders. At the time of writing, COVID-19 is affecting some 143 countries worldwide and there have been over 200,000 reported cases. As testing for COVID-19 has been limited, it is estimated that the true prevalence of COVID-19 is far greater than the situation reports have stated.

WHO has issued information and guidance with a view to reducing the spread of COVID-19 and controlling the pandemic. This information has included correcting misinformation about COVID-19.

The World Federation of Chiropractic (WFC) has supported WHO in its advice and recommendations and on March 17, 2020 issued an advice note to the worldwide chiropractic profession.

One of the key messages contained in the WFC advice note highlighted the lack of credible, scientific evidence supporting claims of effectiveness of spinal adjustment / manipulation in boosting immunity and strengthening the immune system. Immunity is defined as the ability of an organism to resist disease, either through the activities of specialized blood cells or antibodies produced by them in response to natural exposure or inoculation, or by the injection of antiserum, or the transfer of antibodies from a mother to her baby via the placenta or breast milk.

Related Posts

This rapid review considers materials the WFC is aware have been cited in support of claims of effectiveness for spinal adjustment / manipulation in conferring or enhancing immunity.

1. Pero R, Flesia J, (1986) University of Lund, Sweden Citation: None available.

Overview: It has been reported that in 1986 Dr Ronald Pero, a Professor of Medicine in Environmental Health at New York State University, collaborated with Dr Joseph Flesia, a basic science researcher and chiropractor. Reports state that subjects receiving chiropractic care (n=107) had a 200% greater immune competence than those who had not received chiropractic care and a 400% greater immune system competence than those with cancer or other serious disease.

Response: Numerous attempts have failed to retrieve this study. Without the original study to review, no scientific assessment of its claims can be made. Therefore, the “Pero and Flesia” study does not constitute credible, scientific evidence that spinal adjustment / manipulation enhances or confers immunity nor should it be used as a basis to provide care.

2. Enhanced phagocytic cell respiratory burst

Citation: Brennan PC, Kokjohn K, Kaltinger CJ, Lohr GE, Glendening C, Hondras MA, McGregor M, Triano JJ. Enhanced phagocytic cell respiratory burst induced by spinal manipulation: potential role of substance P. J Manipulative Physiol Ther. 1991 Sep;14(7):399-408. PMID:1719112. https://www.ncbi.nlm.nih.gov/pubmed/1719112

Overview: This study examined the effect of spinal manipulation on the respiratory burst of polymorphonuclear neutrophils (PMN) and monocytes in asymptomatic adults. The investigators found changes in levels of substance P in subjects who underwent spinal manipulation but not in subjects who underwent sham manipulation.

Response: The clinical meaning of the study?s results regarding cellular activity is not known. No clinical research has been performed in this area. Therefore, it is not known if these observations have any effect on human health. This report does not constitute credible, scientific evidence that spinal adjustment /

2

manipulation enhances or confers immunity.

3. Enhanced in-vitro interleukin-2 production following spinal manipulation

Citation: Teodorczyk-Injeyan JA, Injeyan HS, McGregor M, Harris GM, Ruegg R. Enhancement of in vitro interleukin-2 production in normal subjects following a single spinal manipulative treatment. Chiropr Osteopat. 2008 May 28;16:5. doi: 10.1186/1746-1340-16-5. PMID: 18507834; PMCID: PMC2423359.https://www.ncbi.nlm.nih.gov/pubmed/18507834

Overview: The purpose of this study was to report on spinal manipulation-related changes in the production of the immunoregulatory cytokine interleukin 2 (IL-2) in asymptomatic adults. This study found a short-term increase in IL-2 with spinal manipulative intervention, with or without cavitation.

Response: Theclinicalmeaningoftheseinvitroobservationsofcellularactivityonhumanhealthisnot known. No clinical research has subsequently been performed in this area.

4. Interleukin-2-regulated in vitro antibody production following single spinal manipulative treatment.

Citation: Teodorczyk-Injeyan JA, McGregor M, Ruegg R, Injeyan HS. Interleukin 2-regulated in vitro antibody production following a single spinal manipulative treatment in normal subjects. Chiropr Osteopat. 2010 Sep 8;18:26. doi: 10.1186/1746-1340-18-26. PMID: 20825650; Central PMCID: PMC2945351.https://www.ncbi.nlm.nih.gov/pubmed/20825650

Overview: The purpose of this study was to determine if spinal manipulation-related augmentation of in vitro interleukin-2 synthesis in asymptomatic adults is associated with the modulation of interleukin 2-dependent and/or interleukin-2-induced humoral immune response. While the augmentation of IL-2 induced IgG or IgM synthesis in subjects receiving spinal manipulation, the amount did not exceed the physiological range of normal human response.

Response: The clinical meaning of these in vitro observations of cellular activity on human health is not known. No clinical research has been performed in this area. Further, the authors state “The clinical significance of the elevated responsiveness to IL-2 demonstrated in this in vitro study is presently unclear.”

5. Effects of specific upper cervical adjustments on CD4 counts in HIV positive patients.

Citation: Hightower BC, Pfleger B, Selano J. The Effects of Specific Upper Cervical Adjustments on the CD4 Counts of HIV Positive Patients. Chiropractic Research Journal 1994 ;3(1):32-39. No PubMed ID available ? this publication is not indexed by PubMed https://www.chiroindex.org/?search_page=articles&action=&articleId=5619

Overview: This project sought to demonstrate if upper cervical specific adjustments have a profound effect on the physiology, serology and immunology of HIV positive individuals. No statistically significant differences between the treatment and control group were found.

Response: With only 5 subjects in the experimental treatment group, no description of how the study was conducted or analyzed, and no reporting of absolute change in CD4 values, these results are highly questionable. Further, the authors state “…it must be noted that we cannot generalize our findings to the general population.” The clinical meaning of these in vitro observations of cellular activity on human health is not known.

6. Reports of decreased mortality in chiropractic/osteopathic patients during flu epidemics. Citation: None

Overview: It is claimed that the treatment of patients by chiropractors during the influenza pandemic of 1918 resulted in fewer deaths than those treated by medical doctors.

Response: These narrative reports of historical events do not equate to scientific studies. Their lack of methodological structure or data analysis is likely to have resulted in incomplete information and a high likelihood of bias. We note that even those who have written about these events in a positive light

3

(https://doi.org/10.7556/jaoa.2013.036) concede that there is no way to tell if these observations can be attributed to manual medicine and care philosophy or ?statistical issues of reporting?. These various reports do not provide the necessary evidence to justify the use of spinal adjustment / manipulation for infectious diseases.

7. Effects induced by spinal manipulative therapy on the immune and endocrine system Citation: Colombi A, Testa M. The effects induced by spinal manipulative therapy on the immune and

endocrine systems. Medicina 2019; 53:448. doi 10.3390/medicina55080448.

Overview: This was a narrative review of the available literature that aimed to provide an overview of the available evidence supporting the biological plausibility of high-velocity, low-amplitude thrust on the immune-endocrine system. Following a search, 4 studies were retrieved studying the effect of spinal manipulation on the immune system.

Response: The authors concluded that “While spinal manipulation may stimulate the neuroimmunoendocrine system, the evidence supporting a biological account for the application of high-velocity, low-amplitude thrust manipulation in clinical practice is mixed and conflicting.” It also concluded that the clinical relevance of most of the studies remained unanswered as they were conducted on healthy subjects. This study supports that there is no current basis for which to provide spinal adjustment / manipulation for the purpose of conferring or enhancing immunity.

Conclusion

No credible, scientific evidence that spinal adjustment / manipulation has any clinically relevant effect on the immune system was found. Available studies have small sample sizes and a lack of symptomatic subjects.

At the time of writing, there exists no credible, scientific evidence that would permit claims of effectiveness for conferring or enhancing immunity through spinal adjustment / manipulation to be made in communications by chiropractors.

In the event that new scientific evidence emerges, it will be critically appraised using scientific methods of analysis.

Acknowledgments

The WFC is grateful to the Research Committee for its work in compiling this rapid review: Greg Kawchuk DC, PhD (Chair)
Christine Goertz DC, PhD (Vice-Chair)
Iben Axén DC, PhD

Martin Descarreaux DC, PhD
Simon French B.App.Sci (Chiro), MPH, PhD Mitch Haas MA, DC
Jan Hartvigsen DC, PhD
Carolina Kolberg BSc (Chiro), PhD Michele Maiers DC, MPH, PhD

Post Disclaimer

Professional Scope of Practice *

The information herein on "Manipulation and Immunity: WHO & WFC Immediately Response" is not intended to replace a one-on-one relationship with a qualified health care professional, licensed physician, and is not medical advice. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.

Our information scope is limited to chiropractic, musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present clinical collaboration with specialists from a wide array of disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system.

Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and support, directly or indirectly, our clinical scope of practice.*

Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.

We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.

We are here to help you and your family.

Blessings

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, ATN*

email: coach@elpasofunctionalmedicine.com

Licensed in: Texas & New Mexico*

Again  We Welcome You¸

Our Purpose & Passions: I am a Doctor of Chiropractic specializing in progressive, cutting-edge therapies and functional rehabilitation procedures focused on clinical physiology, total health, practical strength training, and complete conditioning. We focus on restoring normal body functions after neck, back, spinal and soft tissue injuries.

We use Specialized Chiropractic Protocols, Wellness Programs, Functional & Integrative Nutrition, Agility & Mobility Fitness Training, and Rehabilitation Systems for all ages.

As an extension to effective rehabilitation, we too offer our patients, disabled veterans, athletes, young and elder a diverse portfolio of strength equipment, high-performance exercises, and advanced agility treatment options. We have teamed up with the cities premier doctors, therapists, and trainers to provide high-level competitive athletes the possibilities to push themselves to their highest abilities within our facilities.

We’ve been blessed to use our methods with thousands of El Pasoans over the last three decades allowing us to restore our patients’ health and fitness while implementing researched non-surgical methods and functional wellness programs.

Our programs are natural and use the body’s ability to achieve specific measured goals, rather than introducing harmful chemicals, controversial hormone replacement, unwanted surgeries, or addictive drugs. We want you to live a functional life that is fulfilled with more energy, a positive attitude, better sleep, and less pain. Our goal is to ultimately empower our patients to maintain the healthiest way of living.

With a bit of work, we can achieve optimal health together, no matter the age or disability.

Join us in improving your health for you and your family.

It’s all about: LIVING, LOVING & MATTERING!

Welcome & God Bless

EL PASO LOCATIONS

Central:
6440 Gateway East, Ste B
Phone: 915-850-0900

East Side:
11860 Vista Del Sol, Ste 128
Phone: 915-412-6677A

Clinic Location 1

Address: 11860 Vista Del Sol Dr Suite 128
El Paso, TX 79936
Phone
: (915) 850-0900
EmailSend Email
WebDrAlexJimenez.com

Clinic Location 2

Address: 6440 Gateway East, Building B
El Paso, TX 79905
Phone: (915) 850-0900
EmailSend Email
WebElPasoBackClinic.com

Clinic Location 3

Address: 1700 N Zaragoza Rd # 117
El Paso, TX 79936
Phone: (915) 850-0900
EmailSend Email
WebChiropracticScientist.com

Push As Rx & Rehab

Address: 6440 Gateway East, Building B
El Paso, TX 79905
Phone
: (915) 412-6677
EmailSend Email
WebPushAsRx.com

Push 24/7

Address: 1700 E Cliff Dr
El Paso, TX 79902
Phone
: (915) 412-6677
EmailSend Email
WebPushAsRx.com

EVENTS REGISTRATION: Live Events & Webinars*

(Come Join Us & Register Today)

Call (915) 850-0900 Today!

Rated Top El Paso Doctor & Specialist by RateMD* | Years 2014, 2015, 2016, 2017, 2018, 2019, 2020 & 2021

Best Chiropractor In El Paso

Additional Online Links & Resources (Available 24/7)

  1. Online Appointments or Consultations:  https://bit.ly/Book-Online-Appointment
  2. Online Physical Injury / Accident Intake Form:  https://bit.ly/Fill-Out-Your-Online-History
  3. Online Functional Medicine Assessment:  https://bit.ly/functionmed

Disclaimer *

The information herein is not intended to replace a one-on-one relationship with a qualified health care professional, licensed physician, and is not medical advice. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional. Our information scope is limited to chiropractic, musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present clinical collaboration with specialists from a wide array of disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system. Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and support, directly or indirectly, our clinical scope of practice.* Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.

We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, ATN*

email: coach@elpasofunctionalmedicine.com

phone: 915-850-0900

Licensed in Texas & New Mexico *

Post Disclaimer

Professional Scope of Practice *

The information herein on "Manipulation and Immunity: WHO & WFC Immediately Response" is not intended to replace a one-on-one relationship with a qualified health care professional, licensed physician, and is not medical advice. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.

Our information scope is limited to chiropractic, musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present clinical collaboration with specialists from a wide array of disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system.

Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and support, directly or indirectly, our clinical scope of practice.*

Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.

We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.

We are here to help you and your family.

Blessings

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, ATN*

email: coach@elpasofunctionalmedicine.com

Licensed in: Texas & New Mexico*