Testing For Immunologic Reactions

Share

Food allergies and sensitivities are more prevalent and are a problem that clinicians are beginning to look into more seriously. Nearly 20% of individuals have food reactions, 4% of those being an immune-mediated response. These food sensitivities can cause symptoms immediately or days after ingestion. Frequently reported symptoms include inflammation, headaches, joint pain, hives, fatigue, and more. 

Immunologic Reactions

Immunologic reactions are either immediate or delayed and can be broken down further and classified into 4 separate categories. Type 1, Type 2, Type 3, and Type 4. 

Type 1: an IgE antibody-mediated reaction. This is an immediate hypersensitivity reaction occurring 2 hours or less once exposed to the antigen. Example: eating strawberries and breaking out in hives. Antigens bind to IgE antibodies and release chemical mediators like histamine.

Type 2: Cytotoxic hypersensitivity. This is an antibody-mediated response to IgG and IgM. This reaction is delayed, occurring 2 hours or several days after being exposed. This occurrence is seen when antibodies bind to either self-antigens or foreign antibodies, leading to killer-cell activity. 

Type 3: Immune Complex-mediated reaction. This is also a delayed hypersensitivity and occurs up to weeks post-exposure. In this instance, the immune system creates too many IgG antibodies to a specific food. 

Type 4: This is the cell-mediated form of delayed hypersensitivity. This can be the most serious and cause T-cells to be stimulated by cytokines. Later, these cytokines activate and induce an immune complex formation. 

Testing For Sensitivities

There are several ways to test delayed and immediate sensitivities. One of the most common and frequently talked about is the Prick Test. This test is commonly used by allergists and is performed on the back or forearm of the patient. A small scratch is made and an allergen is inserted. If the spot has a reaction, this translates to a sensitivity. 

An intradermal test is similar to the prick test but instead of inserting the allergen into a scratch, a small amount is injected below the skin. 

The elimination diet is a great place to start when determining if a patient has a food sensitivity. They eliminate the food they think is causing a reaction and record their symptoms over a period of 90 days without ingesting that specific food. 

A RAST test is performed via serum, which is a safe way to test for IgE antibodies in those who may have too severe of a reaction to a prick or intradermal test. 

 

Below is an example of a food sensitivity test we use that tests for IgG and IgA Antibodies with the option of testing for an IgE Allergen: 

It is recommended to record a detailed food diary along with symptoms before having a sensitivity test performed. This will allow the practitioner to see which test is best for you and make a specific plan. Additionally, an IgG antibody test also provides insight to the practitioner if the individuals may be suffering from leaky gut

References: 

Grisanti , Ronald. “Interpretation and Treatment of Food Allergy/Sensitivity/Intolerance Testing.” Functional Medicine University. 11 May 2020, www. functionalmedicineuniversity.com/members/ 465. cfm.

 

The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.  

Post Disclaimer

Professional Scope of Practice *

The information herein on "Testing For Immunologic Reactions" is not intended to replace a one-on-one relationship with a qualified health care professional, or licensed physician, and is not medical advice. We encourage you to make your own healthcare decisions based on your research and partnership with a qualified healthcare professional.

Blog Information & Scope Discussions

Our information scope is limited to Chiropractic, musculoskeletal, physical medicines, wellness, contributing etiological viscerosomatic disturbances within clinical presentations, associated somatovisceral reflex clinical dynamics, subluxation complexes, sensitive health issues, and/or functional medicine articles, topics, and discussions.

We provide and present clinical collaboration with specialists from a wide array of disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system.

Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and support, directly or indirectly, our clinical scope of practice.*

Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.

We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez DC or contact us at 915-850-0900.

We are here to help you and your family.

Blessings

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, ATN*

email: coach@elpasofunctionalmedicine.com

Licensed in: Texas & New Mexico*

Dr. Alex Jimenez DC, MSACP, CIFM*, IFMCP*, ATN*, CCST
My Digital Business Card

Recent Posts

Cold Fingers Causes: EP’s Chiropractic Functional Clinic

In cold weather, it's normal to experience cold hands and fingers. But if there is… Read More

January 27, 2023

Dr. Alex Jimenez Presents: The Impact Of Stress (Part 2)

https://youtu.be/J2u4LV-DCQA?t=1188 Introduction Dr. Alex Jimenez, D.C., presents how chronic stress can impact the body and… Read More

January 27, 2023

Jaw Clenching: EP’s Chiropractic Functional Medicine Team

Bruxism is an abnormal jaw clenching or grinding of the teeth, either while awake or… Read More

January 26, 2023

Dr. Alex Jimenez Presents: The Impact Of Stress

https://youtu.be/J2u4LV-DCQA Introduction Dr. Alex Jimenez, D.C., presents how stress can impact many individuals and correlate… Read More

January 26, 2023

Trapped Sciatic Nerve In or Around Hamstrings: Chiropractic Clinic

Hamstring syndrome is a condition where the sciatic nerve gets pinched between the hamstring muscles… Read More

January 25, 2023

Dr. Alex Jimenez Presents: How Hypertension Is Explained (Part 2)

https://youtu.be/DmTGagbkPzg?t=1064 Introduction Dr. Alex Jimenez, D.C., presents how hypertension affects the human body and how… Read More

January 25, 2023