Dr. Alex Jimenez, El Paso's Chiropractor
I hope you have enjoyed our blog posts on various health, nutritional and injury related topics. Please don't hesitate in calling us or myself if you have questions when the need to seek care arises. Call the office or myself. Office 915-850-0900 - Cell 915-540-8444 Great Regards. Dr. J

Proactive Therapy For Dyslipidemia

The “pill for every ill” therapeutic approach is not enough to ensure its health improvement. In fact, ACC/AHA clinical guidelines are more interested in the risk evaluation and prevention of cardiovascular disease. Consequently, this new perspective sets the pathway for implementing a proactive therapy to treat dyslipidemia, metabolic syndrome, and other comorbidities.

Proactive therapy: Look for other treatments!

Statin therapy is the cornerstone of lipid-lowering therapy (LLT) due to the benefits of lowering cholesterol and LDL-C levels. In fact, statin therapy is associated with preventing primary and secondary atherosclerotic cardiovascular disease (ASCVD). However, numerous patients treated with statin still experience CV events and statin-related secondary effects.

PCSK9

New treatments to lower LDL-C levels have been proposed, one being monoclonal antibodies targeted to inhibit proprotein convertase subtilisin/Kexin type 9 (PCSK9). Currently, there are two FDA-approved therapies to treat heterozygous familial hypercholesterolemia, alirocumab, and Evolocumab. Also, Evolocumab indicated for homozygous familial hypercholesterolemia. Conversely, each treatment’s application derives from the “test don’t guess” approach, focusing on providing personalized treatment.

Medical, nutritional treatment

The inclusion of different nutritional approaches to reduce CVD risk have been the focal point of many research investigation in the last 10 years. Consequently, the “avoid the salt” approach is no longer the only tool under clinicians’ belt.

Genetics, Dyslipidemia, and Cardiovascular Disease

Mediterranean Diet: The cardioprotective effects associated with MD are mediated by collective mechanisms such as Improved vascular function, reduced inflammation, lower ROS levels, enhances NO utilization, improved lipid profiles. All of these mechanisms reflect on improved cardiovascular health.
Plant-based Diet: A low-frequency consumption of animal foods defines it. The inclusion of high-quality plant foods like whole grains, fruits, vegetables, and nuts is associated with lower cardiovascular risk frequency and better outcomes. The overall health benefits are reflected in the maintenance of a healthy weight, enhancement of glycemic control, improvement of lipid profile, blood pressure reduction, decreased inflammation, and improved gut microbial profile.
Low-fat Diet: A wide variety of Low-fat diets have been used in trials and proven beneficial. In a randomized controlled trial with 48,835 postmenopausal women aged 50–79 y; 40% were randomly assigned to a low-fat dietary pattern intervention (target of 20% of energy from fat), and 60% were randomly assigned to a usual diet comparison group. This trial resulted in a risk reduction of cardiac heart disease and lower stroke risk.

Proactive risk evaluation: look for other markers.

As mentioned before, patients with statin therapy may experience CV events. Consequently, this makes us think that maybe we are not considering the whole ecosystem of CVD. LDL- C is an independent factor of cardiovascular disease. However, LDL-C levels are not elevated in patients with coronary heart disease (CHD). Therefore, to assess CVD risk, we might want to look at lipoprotein fractions:

Apolipoproteins

ApoB: is present in small dense LDL particles, intermediate-density lipoprotein, and very-low-density lipoprotein. It reflects the total number of atherogenic particles because one particle of Apo B is present in each one of these molecules. ApoB has another subtype, ApoB-48 can be found in dietary triglycerides and free cholesterol from the gut lumen.

ApoA: has two subtypes, ApoA-1 and ApoA-II. ApoA-1 is the main constituent of HDL, which removes excess cholesterol from tissues. Besides, ApoA-II inhibits hepatic and lipoprotein lipase by reducing plasma HDL levels.

ApoB/ApoA-1 ratio represents the balance between atherogenic and anti-atherogenic cholesterol balance in plasma. In fact, this marker is a vital predictor of myocardial infarction (MI) risk, these conclusions were found in large studies such as AMORIS (Apolipoprotein-related MOrtality RISk). Other large studies, like INTERHEART and PRIME, concluded that ApoB/ApoA-1 ratio was a superior marker to estimate acute MI risk compared to other cholesterol ratios.

TMA-O

Trimethylamine oxidase is the metabolized form of Trimethylamine (TMA), a tertiary amine where three methyl groups surround the central nitrogen atom. TMA is produced by the human gut’s bacteria and then metabolized to TMA-O by flavin monooxygenase- 3 (FMO) enzyme activity in the liver. TMAO is implicated in the formation of atherosclerotic plaque by induction of upregulation of macrophage scavenger receptors’ expression.

Besides, TMAO has been shown to inhibit reverse cholesterol transport (RCT), the mechanism through which cholesterol is removed from peripheral macrophages and transported to the liver, recycled for cholesterol synthesis.

Theories support the idea that this CVD risk marker can be influenced by dysbiosis since elevated TMA levels are associated with higher amounts of Firmicutes. Therefore, the treatment of regulating the microbiome is essential for the management of this marker.

Proactive tip: how does inflammation affect the dyslipidemia ecosystem?

Assessing CVD risk has to take into account the interplay between inflammation and the development of this condition. Recently, the use of high sensitivity C- reactive protein (CRP) has been proposed as a marker for circulation and inflammation.

As a reactive phase protein, CRP is induced by IL-6, IL-1b, and TNF-a in the liver. However, CRP levels are detectable in the vessel walls in the early stages of atherogenesis. The interplay between LDL and CRP induces a proinflammatory response by promoting the transformation of macrophages into foam cells. Also, this complex contributes to the progression of atherosclerosis and tissue damage.

Besides this, nitric oxide can be inhibited by CRP, leading to endothelial dysfunction and hypertension. Adding to this, CRP can create the perfect stroke by activating the NF-KB pathway.

Advanced body composition assessment

Body composition is a very important part of the patient’s environment, Fat distribution plays a vital role in the risk evaluation of CVD. Therefore in El Paso Functional Clinic we have the best piece of equipment to help you get on the right track.

What Is Body Composition?

The fact that CVD is the most common cause of death in the United States is disturbing. However, the work has to be done, and preventing CVD is the next step. The proactive way to treat dyslipidemia includes assessment, dietic therapy, and stress management. Improving the ecosystem of a patient will always provide a better outcome in chronic conditions. – Ana Paola Rodríguez Arciniega, MS

References

Kaddoura, Rasha et al. “Efficacy and safety of PCSK9 monoclonal antibodies: an evidence-based review and update.” Journal of drug assessment vol. 9,1 129-144. 11 Aug. 2020, doi:10.1080/21556660.2020.1801452

Jun, Ji Eun et al. “ApoB/ApoA-I ratio is independently associated with carotid atherosclerosis in type 2 diabetes mellitus with well-controlled LDL cholesterol levels.” The Korean journal of internal medicine vol. 33,1 (2018): 138-147. doi:10.3904/kjim.2017.396

Badimon, Lina et al. “C-Reactive Protein in Atherothrombosis and Angiogenesis.” Frontiers in immunology vol. 9 430. 2 Mar. 2018, doi:10.3389/fimmu.2018.00430

Satija, Ambika, and Frank B Hu. “Plant-based diets and cardiovascular health.” Trends in cardiovascular medicine vol. 28,7 (2018): 437-441. doi:10.1016/j.tcm.2018.02.004

Widmer, R Jay et al. “The Mediterranean diet, its components, and cardiovascular disease.” The American journal of medicine vol. 128,3 (2015): 229-38. doi:10.1016/j.amjmed.2014.10.014

Online Appointments or Consultations:  bit.ly/Book-Online-Appointment

Online Physical Injury / Accident Intake Form: bit.ly/Fill-Out-Your-Online-History

Online Functional Medicine Assessment: bit.ly/functionmed

Disclaimer

The information herein is not intended to replace a one-on-one relationship with a qualified health care professional, licensed physician, and not medical advice. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional. Our information scope is limited to chiropractic, musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present clinical collaboration with specialists from a wide array of disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the musculoskeletal system’s injuries or disorders. Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and support, directly or indirectly, our clinical scope of practice.* Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request. We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us 915-850-0900 Read More…

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*

email: coach@elpasofunctionalmedicine.com
phone: 915-850-0900
Licensed in Texas & New Mexico

Post Disclaimer

Professional Scope of Practice *

The information herein on "Proactive Therapy For Dyslipidemia" is not intended to replace a one-on-one relationship with a qualified health care professional or licensed physician and is not medical advice. We encourage you to make healthcare decisions based on your research and partnership with a qualified healthcare professional.

Blog Information & Scope Discussions

Our information scope is limited to Chiropractic, musculoskeletal, acupuncture, physical medicines, wellness, contributing etiological viscerosomatic disturbances within clinical presentations, associated somatovisceral reflex clinical dynamics, subluxation complexes, sensitive health issues, and/or functional medicine articles, topics, and discussions.

We provide and present clinical collaboration with specialists from various disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system.

Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and directly or indirectly support our clinical scope of practice.*

Our office has reasonably attempted to provide supportive citations and has identified the relevant research studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.

We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez, DC, or contact us at 915-850-0900.

We are here to help you and your family.

Blessings

Dr. Alex Jimenez DC, MSACP, RN*, CCST, IFMCP*, CIFM*, ATN*

email: coach@elpasofunctionalmedicine.com

Licensed as a Doctor of Chiropractic (DC) in Texas & New Mexico*
Texas DC License # TX5807, New Mexico DC License # NM-DC2182

Licensed as a Registered Nurse (RN*) in Florida
Florida License RN License # RN9617241 (Control No. 3558029)
Compact Status: Multi-State License: Authorized to Practice in 40 States*

Presently Matriculated: ICHS: MSN* FNP (Family Nurse Practitioner Program)

Dr. Alex Jimenez DC, MSACP, RN* CIFM*, IFMCP*, ATN*, CCST
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Our Purpose & Passions: I am a Doctor of Chiropractic specializing in progressive, cutting-edge therapies and functional rehabilitation procedures focused on clinical physiology, total health, practical strength training, and complete conditioning. We focus on restoring normal body functions after neck, back, spinal and soft tissue injuries.

We use Specialized Chiropractic Protocols, Wellness Programs, Functional & Integrative Nutrition, Agility & Mobility Fitness Training, and Rehabilitation Systems for all ages.

As an extension to effective rehabilitation, we too offer our patients, disabled veterans, athletes, young and elder a diverse portfolio of strength equipment, high-performance exercises, and advanced agility treatment options. We have teamed up with the cities premier doctors, therapists, and trainers to provide high-level competitive athletes the possibilities to push themselves to their highest abilities within our facilities.

We’ve been blessed to use our methods with thousands of El Pasoans over the last three decades allowing us to restore our patients’ health and fitness while implementing researched non-surgical methods and functional wellness programs.

Our programs are natural and use the body’s ability to achieve specific measured goals, rather than introducing harmful chemicals, controversial hormone replacement, unwanted surgeries, or addictive drugs. We want you to live a functional life that is fulfilled with more energy, a positive attitude, better sleep, and less pain. Our goal is to ultimately empower our patients to maintain the healthiest way of living.

With a bit of work, we can achieve optimal health together, no matter the age or disability.

Join us in improving your health for you and your family.

It’s all about: LIVING, LOVING & MATTERING!

Welcome & God Bless

EL PASO LOCATIONS

East Side: Main Clinic*
11860 Vista Del Sol, Ste 128
Phone: 915-412-6677

Central: Rehabilitation Center
6440 Gateway East, Ste B
Phone: 915-850-0900

North East Rehabilitation Center
7100 Airport Blvd, Ste. C
Phone: 915-412-6677

Dr. Alex Jimenez DC, MSACP, CIFM, IFMCP, ATN, CCST
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Clinic Location 1

Address: 11860 Vista Del Sol Dr Suite 128
El Paso, TX 79936
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Additional Online Links & Resources (Available 24/7)

  1. Online Appointments or Consultations:  bit.ly/Book-Online-Appointment
  2. Online Physical Injury / Accident Intake Form:  bit.ly/Fill-Out-Your-Online-History
  3. Online Functional Medicine Assessment:  bit.ly/functionmed

Disclaimer *

The information herein is not intended to replace a one-on-one relationship with a qualified health care professional, licensed physician, and is not medical advice. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional. Our information scope is limited to chiropractic, musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present clinical collaboration with specialists from a wide array of disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system. Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and support, directly or indirectly, our clinical scope of practice.* Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.

We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, ATN*

email: coach@elpasofunctionalmedicine.com

phone: 915-850-0900

Licensed in Texas & New Mexico *

Dr. Alex Jimenez DC, MSACP, CIFM, IFMCP, ATN, CCST
My Digital Business Card

Post Disclaimer

Professional Scope of Practice *

The information herein on "Fighting Inflammation Naturally *Chiropractic Care* | El Paso, Tx (2023)" is not intended to replace a one-on-one relationship with a qualified health care professional or licensed physician and is not medical advice. We encourage you to make healthcare decisions based on your research and partnership with a qualified healthcare professional.

Blog Information & Scope Discussions

Our information scope is limited to Chiropractic, musculoskeletal, acupuncture, physical medicines, wellness, contributing etiological viscerosomatic disturbances within clinical presentations, associated somatovisceral reflex clinical dynamics, subluxation complexes, sensitive health issues, and/or functional medicine articles, topics, and discussions.

We provide and present clinical collaboration with specialists from various disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system.

Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and directly or indirectly support our clinical scope of practice.*

Our office has reasonably attempted to provide supportive citations and has identified the relevant research studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.

We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez, DC, or contact us at 915-850-0900.

We are here to help you and your family.

Blessings

Dr. Alex Jimenez DC, MSACP, RN*, CCST, IFMCP*, CIFM*, ATN*

email: coach@elpasofunctionalmedicine.com

Licensed as a Doctor of Chiropractic (DC) in Texas & New Mexico*
Texas DC License # TX5807, New Mexico DC License # NM-DC2182

Licensed as a Registered Nurse (RN*) in Florida
Florida License RN License # RN9617241 (Control No. 3558029)
Compact Status: Multi-State License: Authorized to Practice in 40 States*

Presently Matriculated: ICHS: MSN* FNP (Family Nurse Practitioner Program)

Dr. Alex Jimenez DC, MSACP, RN* CIFM*, IFMCP*, ATN*, CCST
My Digital Business Card